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Methadone Intoxication in a Child: Toxic Encephalopathy?

2006-07Journal article Open access
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dc.contributor.authorAnselmo, M
dc.contributor.authorCampos Rainho, A
dc.contributor.authorVale, MC
dc.contributor.authorEstrada, J
dc.contributor.authorValente, R
dc.contributor.authorCorreia, M
dc.contributor.authorVieira, JP
dc.contributor.authorBarata, D
dc.date.accessioned2015-11-13T11:51:59Z
dc.date.available2015-11-13T11:51:59Z
dc.date.issued2006-07
dc.description.abstractMethadone is used in the treatment of opioid addiction. Acute intoxication can lead to severe consequences and can even be lethal. In several case reports and small series, a presumably toxic leukoencephalopathy is described resulting from inhalation of heroin. We present the case of a 3-year-old boy who ingested methadone accidentally. In a coma with acute obstructive hydrocephalus owing to massive cerebellar edema and supratentorial lesions, he was successfully treated with methylprednisolone and cerebrospinal fluid external drainage. To our knowledge, this is the first report of an encephalopathy associated with synthetic opioid intoxication.pt_PT
dc.identifier.citationJ Child Neurol. 2006 Jul;21(7):618-20.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2343
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSage Publicationspt_PT
dc.subjectAnalgesics, Opioid/poisoningpt_PT
dc.subjectBrain Diseases/chemically inducedpt_PT
dc.subjectBrain Diseases/pathologypt_PT
dc.subjectBrain Diseases/therapypt_PT
dc.subjectMethadone/poisoningpt_PT
dc.subjectNeurotoxicity Syndromes/etiologypt_PT
dc.subjectNeurotoxicity Syndromes/therapypt_PT
dc.subjectChild, Preschoolpt_PT
dc.subjectCase Reportspt_PT
dc.subjectHDE NEU PEDpt_PT
dc.subjectHDE UCI PEDpt_PT
dc.titleMethadone Intoxication in a Child: Toxic Encephalopathy?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage620pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage618pt_PT
oaire.citation.volume21pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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