Publication
Pneumocystosis Pneumonia: A Comparison Study Between HIV and Non-HIV Immunocompromised Patients
| dc.contributor.author | Rego de Figueiredo, I | |
| dc.contributor.author | Vieira Alves, R | |
| dc.contributor.author | Drummond Borges, D | |
| dc.contributor.author | Torres, M | |
| dc.contributor.author | Lourenço, F | |
| dc.contributor.author | Antunes, AM | |
| dc.contributor.author | Gruner, H | |
| dc.contributor.author | Panarra, A | |
| dc.date.accessioned | 2019-10-11T09:56:34Z | |
| dc.date.available | 2019-10-11T09:56:34Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Pneumocystis pneumonia (PCP) is caused by the fungus Pneumocystis jirovecii, and its incidence has been on the rise in immunosuppressed patients without HIV. We performed a cross sectional study in patients with PCP and assessed demographic, clinical presentation and outcome measures such as mechanical ventilation and mortality differences between HIV and non-HIV patients. The two groups were statistically significantly different, with the HIV group being younger (45.5 years vs 55.9 years, p-value 0.001) and mostly composed of male patients (69% vs 31%, p-value <0.001). Also, the HIV patients had higher percentage of respiratory complaints (90% vs 68%, p-value 0.02) and lactate dehydrogenase elevation (73% vs 40%, p-value 0.001). In contrast, non-HIV patients had worse outcomes with higher incidence of invasive mechanical ventilation (23% vs 46%, p-value 0.005) and in-hospital mortality (13% vs 37%, p-value 0.002). These results reflect the literature and should raise awareness to a potentially fatal medical situation of increasing incidence. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Pulmonology. 2019 Sep - Oct;25(5):271-274. | pt_PT |
| dc.identifier.doi | 10.1016/j.pulmoe.2019.04.003 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/3317 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Elsevier España | pt_PT |
| dc.subject | HCC MED | pt_PT |
| dc.subject | HCC INF | pt_PT |
| dc.subject | Comorbidity | pt_PT |
| dc.subject | Cross-Sectional Studies | pt_PT |
| dc.subject | HIV Infections/epidemiology | pt_PT |
| dc.subject | HIV Infections/immunology | pt_PT |
| dc.subject | Hospital Mortality | |
| dc.subject | Immunocompromised Host | |
| dc.subject | L-Lactate Dehydrogenase/blood | |
| dc.subject | Pneumonia, Pneumocystis/epidemiology | |
| dc.subject | Pneumonia, Pneumocystis/immunology | |
| dc.subject | Pneumonia, Pneumocystis/mortality | |
| dc.subject | Portugal/epidemiology | |
| dc.subject | Respiration, Artificial/statistics & numerical data | |
| dc.subject | Retrospective Studies | |
| dc.title | Pneumocystosis Pneumonia: A Comparison Study Between HIV and Non-HIV Immunocompromised Patients | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 274 | pt_PT |
| oaire.citation.issue | 5 | pt_PT |
| oaire.citation.startPage | 271 | pt_PT |
| oaire.citation.title | Pulmonology | pt_PT |
| oaire.citation.volume | 25 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |